According to the authors, mitragynine “does not have abuse potential and reduces morphine intake” – ostensibly making it an effective treatment option for those suffering at the hands of addictive opiate drugs like morphine.
Unfortunately, these medicinal applications don’t seem to apply to another primary kratom alkaloid, called 7-hydroxymitragynine (or 7-HMG for short). The researchers concluded that, unlike mitragynine, 7-HMG has a “high abuse potential” and “may also increase the intake of other opiates,” given the response it generated with rats during animal trials.
However, it may be necessary to take these findings with a grain of salt, given that 7-HMG only accounts for 2% of kratom’s alkaloid content, while mitragynine represents a whopping 66% .
United States Legislation Involving Kratom Delayed
A final verdict on a large grouping of 57 or more bills intended to crack down on the opioid crisis within the United States – including the notorious SITSA – has been delayed.
Writing on behalf of the American Kratom Association, Public Policy Expert Mac Haddow stated that “Republican Senate Majority Leader Mitch McConnell will likely wait until November to consider any of these opioid bills.” In light of this news, many American kratom users with concerns regarding the plant’s tentative legality will likely be able to put their fears on-hold.
That said, American kratom advocates shouldn’t rest on their laurels, either! Facing mounting pressures from various US institutions including the FDA, kratom’s legality remains hotly contested.
To keep up with US legislation involving kratom, be sure to click here and visit often!
That’s it for this week’s update – thanks for stopping by, and all the best to you and yours!
Hassan, Z., Muzaimi, M., Navaratnam, V., H.M. Yusoff, N., W. Suhaimi, F., Vadivelu, R., Vicknasingam, B., Amato, D., von Hörsten, S., Ismail, N. I. W., Jayabalan, N., I. Hazim, A., M. Mansor, S., & P. Müller, C. (2013). From Kratom to mitragynine and its derivatives: Physiological and behavioural effects related to use, abuse, and addiction (Vol. 37). https://doi.org/10.1016/j.neubiorev.2012.11.012